Being a relatively small city by Mexican standards, it is not possible to get to Orizaba in a commercial flight from a major airline. However, it is possible to reach the city flying to Mexico City International airport and taking a bus directly to Orizaba from the airport.
If you know someone or are alone when travelling to Orizaba, it may be more convenient to fly into Veracruz International Airport in the city of Veracruz. The drive to Orizaba is about 3 hours long, but the roads are fairly well maintained. There are numerous car rental companies in Veracruz.
The reason for flying into Veracruz vice Mexico City is for several reasons:
1) Traffic in Mexico City is notoriously horrible. Veracruz traffic is considerably thinner and easier to manage.
2) The mountain overpass between Orizaba and Mexico City is extremely dangerous, with sharp turns and angles of nearly twenty degrees vertical. During the winter it is nearly inaccesible and not recommended for driving.
Getting to Orizaba by car is easy. From Mexico City, take the Mexico-Veracruz highway. Orizaba is about four hours from Mexico's capital.
Major bus companies (ADO, ADO GL, UNO, AU, etc) offer service to Orizaba. Rates vary according to quality service. Seniors have 50% off when traveling by ADO.
*[url=http://www.uno.com.mx]UNO Bus service. High end quality.[/url]
*[url=http://www.adogl.com.mx]ADO GL Bus service. 1st Class.[/url]
*[url=http://www.ado.com.mx]ADO Bus service. Standard service.[/url]
Orizaba is not reachable by boat.
* very nice, historic and cheap. Right close to centro as well
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